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Anti-14-3-3 zeta Rabbit pAb (100 μl)
| Reactivity: | H,M,R & M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | 14-3-3 protein zeta/delta |
Synonyms: | Protein kinase C inhibitor protein 1, KCIP-1, SEZ-2, Ywhaz, 14-3-3 Delta, 14-3-3 Zeta |
Immunogen: | Recombinant protein corresponding to Mouse 14-3-3 zeta |
Uniprot ID: | P63101 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm |
Predicted MW. / Observed MW. | 28 kDa / 28 kDa |
Product Usage Information
WB | Human, Mouse, Rat | 1: 500-1: 1000 | lung, kidney, brain |
IHC/IF | Mouse, Rat | 1: 500-1: 2000 | brain |
Background
YWHAZ belongs to the 14-3-3 family of proteins which are in charge for checkpoint control, apoptotic & nutrient sensing pathways as well as signal transduction by binding to phosphoserine-containing proteins. This highly conserved and ubiquitously expressed protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. It interacts with IRS1 protein,signifying a role in regulating insulin. YWHAZ function as an adapter protein involved in the regulation of a large spectrum of both general and specialized signaling pathway.
Images
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Western blot analysis of 14-3-3 zeta (GB111023) at dilution of 1: 1000 |
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Immunohistochemistry analysis of paraffin-embedded mouse brain using 14-3-3 zeta (GB111023) at dilution of 1: 2000 |
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Immunohistochemistry analysis of paraffin-embedded rat brain using 14-3-3 zeta (GB111023) at dilution of 1: 2000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
