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Anti-5HT6 Receptor Rabbit pAb (100 μl)
| Reactivity: | H,M,R & M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | 5HT6 Receptor rabbit polyclonal antibody |
Gene Name: | 5-hydroxytryptamine receptor 6 |
Synonyms: | 5-HT-6, 5-HT6, Serotonin receptor 6, Htr6 |
Immunogen: | Recombinant protein corresponding to Mouse 5HT6 Receptor |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane |
Predicted MW. | 47 kDa |
Observed MW. | 47 kDa |
Uniprot ID: | P50406, Q9R1C8, P31388 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | brain, cerebral cortex |
IHC/IF | Mouse, Rat | 1: 600-1: 1200 | corpus striatum, prefrontal lobe |
Background
This gene encodes a protein that belongs to the seven-transmembrane G protein-coupled receptor family of proteins. The encoded protein couples with the Gs alpha subunit and stimulates adenylate cyclase to activate the cyclic AMP-dependent signaling pathway. This receptor is thought to regulate cholinergic neuronal transmission in the brain. Several antidepressants and antipsychotic drugs have a high affinity for this receptor.
Images
 | Western blot analysis of 5HT6 (GB112416) at dilution of 1: 500 |
 | Immunofluorescence of paraffin embedded mouse prefrontal lobe using 5HT6 (GB112416) at dilution of 1: 600 (400x lens) |
 | Immunofluorescence of paraffin embedded rat corpus striatum using 5HT6 (GB112416) at dilution of 1: 600 (250x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
