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Anti-A4GNT Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | A4GNT rabbit polyclonal antibody |
Gene Name: | Alpha-1,4-N-acetylglucosaminyltransferase |
Synonyms: | Alpha4GnT, A4gnt, Alpha 1 4 N acetylglucosaminyltransferase, 4-N-acetylglucosaminyltransferase |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse A4GNT |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 39 kDa |
Observed MW. | 39 kDa |
Uniprot ID: | Q9UNA3, Q14BT6 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | pancreas, kidney, stomach |
Background
Alpha 1,4-N-acetylflucosaminyltransferase (Alpha4Gn-T) mediates the biosynthesis of mucin type glycoprotein (O-glycan). Alpha4Gn-T acts as the key enzyme for the formation of the unique glycan GlcNAcalpha1-4Galbeta1-R, and most efficiently transfers N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans. Alpha4Gn-T is a single-pass type II membrane protein associated with the Golgi apparatus and contains the conserved DXD motif involved in catalytic activity. It is expressed in stomach and pancreas, as well as in gastric cancer cells. Alpha4Gn-T is not expressed in peripheral blood cells, making it a useful biomarker for pancreatic cancer.
Images
 | Western blot analysis of A4gnt (GB112322) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
