Your shopping cart is empty!
| Reactivity: | M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | AC5 rabbit polyclonal antibody |
Gene Name: | Adenylate cyclase type 5 |
Synonyms: | Adenylate cyclase type V, Adenylyl cyclase 5, Adcy5, AC5, ATP pyrophosphate-lyase 5 |
Immunogen: | Recombinant protein corresponding to Mouse AC5 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane |
Uniprot ID: | P84309, Q04400 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 500-1: 1500 | placenta |
Background
This gene encodes a member of the membrane-bound adenylyl cyclase enzymes. Adenylyl cyclases mediate G protein-coupled receptor signaling through the synthesis of the second messenger cAMP. Activity of the encoded protein is stimulated by the Gs alpha subunit of G protein-coupled receptors and is inhibited by protein kinase A, calcium and Gi alpha subunits. Single nucleotide polymorphisms in this gene may be associated with low birth weight and type 2 diabetes.
Images
| Immunohistochemistry of paraffin embedded mouse placenta using ADCY5 (GB111863) at dilution of 1:900 (300x lens) |
| Immunohistochemistry of paraffin embedded rat placenta using ADCY5 (GB111863) at dilution of 1:900 (300x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
