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Anti-ADAR1 Rabbit pAb (100 μl)
| Reactivity: | H |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | ADAR1 rabbit polyclonal antibody |
Gene Name: | Double-stranded RNA-specific adenosine deaminase |
Synonyms: | DRADA, RNA adenosine deaminase 1, Adar, Adar1, 136kDa double stranded RNA binding protein, AGS6, Adenosine deaminase acting on RNA 1 A, Interferon inducible protein 4, RNA adenosine deaminase 1 |
Immunogen: | Recombinant protein corresponding to Mouse ADAR1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 130 kDa |
Observed MW. | 110 kDa |
Uniprot ID: | P55265 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human | 1: 500-1: 1000 | 293T, Jurkat, HepG2, HeLa, DU145 |
Background
ADAR1 is also named as ADAR1, DSRAD, G1P1, IFI4. It convert selected adenosine residues into inosine in substrate RNAs containing a relatively short dsRNA region. The human ADAR1 gene specifies two size forms of RNA-specific adenosine deaminase, an interferon (IFN) inducible ∼150 kDa protein and a constitutively expressed N-terminally truncated ∼110 kDa protein, encoded by transcripts with alternative exon 1 structures that initiate from different promoters. It has 5 isoforms produced by alternative promoter usage and alternative splicing. Defects in ADAR are a cause of dyschromatosis symmetrical hereditaria (DSH).ADAR1 can form respective homodimers, and this association is essential for its enzymatic activities.
Images
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Western blot analysis of ADAR1 (GB111458) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
