Reactivity: | M,R & M,R |
Applications: | WB & IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | Adenylate cyclase type 2 |
Synonyms: | ATP pyrophosphate-lyase 2, Adenylate cyclase type II, Adenylyl cyclase 2, Kiaa1060, AC2, HBAC2, KIAA1060, MGC133314 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse ADCY2 |
Uniprot ID: | Q80TL1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane, Cytoplasm |
Predicted MW. / Observed MW. | 123 kDa / 124 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 300-1: 600 | brain, cerebellum |
IHC/IF | Mouse, Rat | 1: 1000-1: 3000 | hippocampus, kidney, brain |
Background
Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. Down-stream signaling cascades mediate changes in gene expression patterns and lead to increased IL6 production. Functions in signaling cascades downstream of the muscarinic acetylcholine receptors.
Images
Western blot analysis of ADCY2 (GB114825) at dilution of 1: 300 | |
Immunohistochemistry of paraffin embedded mouse Hippocampus using ADCY2 (GB114825) at dilution of 1: 1000 | |
Immunohistochemistry of paraffin embedded rat kidney using ADCY2 (GB114825) at dilution of 1: 1000 | |
Immunofluorescence of paraffin embedded rat kidney using ADCY2 (GB114825) at dilution of 1: 1000 | |
Immunofluorescence of paraffin embedded mouse Brain using ADCY2 (GB114825) at dilution of 1: 1000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |