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Anti-AICDA Rabbit pAb (100 μl)
| Reactivity: | H,M |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | AICDA rabbit polyclonal antibody |
Gene Name: | Single-stranded DNA cytosine deaminase |
Synonyms: | Activation-induced cytidine deaminase, AID, Cytidine aminohydrolase, Aicda, CDA2, HIGM2, Integrated into Burkitt's lymphoma cell line Ramos |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse AICDA |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 24 kDa |
Observed MW. | 24 kDa |
Uniprot ID: | Q9GZX7, Q9WVE0 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse | 1: 500-1: 1000 | lymph gland, spleen |
Background
This gene encodes a RNA-editing deaminase that is a member of the cytidine deaminase family. The protein is involved in somatic hypermutation, gene conversion, and class-switch recombination of immunoglobulin genes. Defects in this gene are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2).
Images
| Western blot analysis of AID (GB112019) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
