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| Reactivity: | M,R & H,M |
| Applications: | WB & IHC |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | AK 1 rabbit polyclonal |
Gene Name: | Adenylate kinase isoenzyme 1 |
Synonyms: | adenylate kinase 1, AK 1, AK1, ATP AMP transphosphorylase 1, Myokinase |
Immunogen: | Recombinant protein corresponding to Mouse AK 1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Predicted MW. | 22 kDa |
Observed MW. | 22 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 1000-1: 2000 | heart, skeletal muscle |
IHC | Human, Mouse | 1: 2000-1: 4000 | kidney |
Background
This gene encodes an adenylate kinase enzyme involved in energy metabolism and homeostasis of cellular adenine nucleotide ratios in different intracellular compartments. This gene is highly expressed in skeletal muscle, brain and erythrocytes. Certain mutations in this gene resulting in a functionally inadequate enzyme are associated with a rare genetic disorder causing nonspherocytic hemolytic anemia. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.
Images
 | Western blot analysis of AK 1 (GB113147) at dilution of 1: 2000 |
| Immunohistochemistry analysis of paraffin-embedded human kidney using AK 1 (GB113147) at dilution of 1: 4000 |
| Immunohistochemistry analysis of paraffin-embedded mouse kidney using AK 1 (GB113147) at dilution of 1: 4000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
