Reactivity: | M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | AK2 rabbit polyclonal |
Gene Name: | Adenylate kinase 2, mitochondrial |
Synonyms: | adenylate kinase 2, ADK2, AK 2, AK2, ATP AMP transphosphorylase 2, EC 2.7.4.3 |
Immunogen: | Recombinant protein corresponding to Mouse AK2 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 26 kDa |
Observed MW. | 26 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 3000-1: 6000 | Liver, kidney, pancreas, stomach |
Background
AK2(Adenylate kinase 2, mitochondrial ) is also named as ADK2 and belongs to the adenylate kinase family. It plays a unique role in energy metabolism and energy transfer by regulating the ATP/ADP rate between the cytoplasma matrix and the mitochondria and it is increased expression during adipocyte and B cell differentiation. AK2 catalyzes the reversible transfer of a phosphoryl group from ATP to AMP. Defects in AK2 are the cause of reticular dysgenesis (RDYS). It has 6 isoforms produced by alternative splicing.
Images
Western blot analysis of AK2 (GB113113) at dilution of 1: 6000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |