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Anti-AKR1C1/AKR1C2 Rabbit pAb (100 μl)
| Reactivity: | H |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | AKR1C1/AKR1C2 rabbit polyclonal |
Gene Name: | Aldo-keto reductase family 1 member C2 |
Synonyms: | 3-alpha-HSD3, Chlordecone reductase homolog HAKRD, Dihydrodiol dehydrogenase 2, DD-2, DD2, DD/BABP, AKR1C2, DDH2, Type III 3-alpha-hydroxysteroid dehydrogenase, MBAB, HBAB |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Human AKR1C1/AKR1C2 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Predicted MW. | 37 kDa |
Observed MW. | 37 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
| WB | Human | 1: 500-1: 1000 | HeLa, HepG2, A549 |
Background
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding two different isoforms have been found for this gene.
Images
 | Western blot analysis of AKR1C1/AKR1C2 (GB112996) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
