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Anti-AKR1D1 Rabbit pAb (100 μl)
| Reactivity: | H,M |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Aldo-keto reductase family 1 member D1-3-ketosteroid 5-beta-reductase)-3-oxosteroid 5-beta-reductase) |
Synonyms: | 3o5bred, AKR1D1, CBAS2, SRD5B1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse AKR1D1 |
Uniprot ID: | Q8VCX1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 37 kDa / 37 kDa |
Product Usage Information
WB | Human, Mouse | 1: 2000-1: 4000 | liver |
Background
Catalyzes the stereospecific NADPH-dependent reduction of the C4-C5 double bond of bile acid intermediates and steroid hormones carrying a delta(4)-3-one structure to yield an A/B cis-ring junction. This cis-configuration is crucial for bile acid biosynthesis and plays important roles in steroid metabolism. Capable of reducing a broad range of delta-(4)-3-ketosteroids from C18 (such as, 17beta-hydroxyestr-4-en-3-one) to C27 (such as, 7alpha-hydroxycholest-4-en-3-one).
Images
| Western blot analysis of AKR1D1 (GB114667) at dilution of 1: 2000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
