Reactivity: | R |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | AKT2 rabbit polyclonal antibody |
Gene Name: | RAC-beta serine/threonine-protein kinase |
Synonyms: | AKT2, v-akt murine thymoma viral oncogene homolog 2, HIHGHH, PKBB, PKBBETA, PRKBB, RAC-BETA, AKT serine/threonine kinase 2 |
Immunogen: | Recombinant protein corresponding to Rat AKT2 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane, Nucleus, Endosome |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Rat | 1: 250-1: 2000 | brain, kidney, lung |
Background
RAC-beta serine/threonine-protein kinase is an enzyme that in humans is encoded by the AKT2 gene. This gene is a putative oncogene encoding a protein belonging to the AKT subfamily of serine/threonine kinases that contain SH2-like (Src homology 2-like) domains. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phosphorylating several known proteins.
Images
Immunohistochemistry of paraffin embedded rat brain using AKT2 (GB11629) at dilution of 1:1000 (200x lens) |
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Immunohistochemistry of paraffin embedded rat brain using AKT2 (GB11629) at dilution of 1:1000 (400x lens) | |
Immunohistochemistry of paraffin embedded rat kidney using AKT2 (GB11629) at dilution of 1:1000 (400x lens) | |
Immunohistochemistry of paraffin embedded rat lung using AKT2 (GB11629) at dilution of 1:1000 (400x lens) | |
Immunofluorescence of paraffin embedded rat lung using AKT2 (GB11629) at dilution of 1:2000 (400x lens) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |