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Anti-AMCase Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | AMCase rabbit polyclonal |
Gene Name: | Acidic mammalian chitinase |
Synonyms: | Acidic mammalian chitinase, AMCase, CHIA, CHIT2, chitinase, acidic, Lung specific protein TSA1902, RP5 1125M8.1, TSA1902, ECF L |
Immunogen: | Recombinant protein corresponding to Mouse AMCase |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 52 kDa |
Observed MW. | 52 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | kidney, lung, stomach |
Background
Degrades chitin and chitotriose. May participate in the defense against nematodes, fungi and other pathogens. Plays a role in T-helper cell type 2 (Th2) immune response. Contributes to the response to IL-13 and inflammation in response to IL-13. Stimulates chemokine production by pulmonary epithelial cells. Protects lung epithelial cells against apoptosis and promotes phosphorylation of AKT1. Its function in the inflammatory response and in protecting cells against apoptosis is inhibited by allosamidin, suggesting that the function of this protein depends on carbohydrate binding. Presence in saliva and gastric juice suggests a function as a digestive enzyme.
Images
 | Western blot analysis of CHIA (GB113637) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
