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| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Glucose-6-phosphate isomerase |
Synonyms: | Autocrine motility factor, g6pi, glucose phosphate isomerase, GNPI, GPI, Neuroleukin, NLK, PGI, PHI, Phosphoglucose isomerase, Phosphohexose isomerase, SA 36, Sperm antigen 36 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse AMF |
Uniprot ID: | P06745 |
Isotype: | lgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 63 kDa / 60 kDa |
Product Usage Information
WB | Human, Mouse, Rat | 1: 300-1: 400 | kidney, heart |
Background
In the cytoplasm, catalyzes the conversion of glucose-6-phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis Besides it's role as a glycolytic enzyme, also acts as a secreted cytokine: acts as an angiogenic factor (AMF) that stimulates endothelial cell motility (By similarity). Acts as a neurotrophic factor, neuroleukin, for spinal and sensory neurons It is secreted by lectin-stimulated T-cells and induces immunoglobulin secretion
Images
| WB analysis of GPI (GB115551). |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
