Reactivity: | R |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | ANKRD1 rabbit polyclonal antibody |
Gene Name: | Ankyrin repeat domain-containing protein 1 |
Synonyms: | Cardiac ankyrin repeat protein, Ankrd1, Cytokine inducible nuclear protein, HA1A2, Liver ankyrin repeat domain 1, MCARP, CARP, bA320F15.2, Ankyrin repeat domain containing protein 1 |
Immunogen: | Recombinant protein corresponding to Mouse ANKRD1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus |
Uniprot ID: | Q8R560 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Rat | 1: 600-1: 1500 | Skeletal muscle |
Background
The protein encoded by this gene is localized to the nucleus of endothelial cells and is induced by IL-1 and TNF-alpha stimulation. May play an important role in endothelial cell activation. Studies in rat cardiomyocytes suggest that this gene functions as a transcription factor. Interactions between this protein and the sarcomeric proteins myopalladin and titin suggest that it may also be involved in the myofibrillar stretch-sensor system.
Images
Immunofluorescence of paraffin embedded rat skeletal muscle using ANKRD1 (GB111571) at dilution of 1:750 (300x lens) | |
Immunofluorescence of paraffin embedded rat skeletal muscle using ANKRD1 (GB111571) at dilution of 1:750 (300x lens) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |