Anti-AP4M1 Rabbit pAb (100 μl)

Anti-AP4M1 Rabbit pAb (100 μl)

Brand: ServiceBio
Cat. #: GB114461-100
Availability: In Stock
$259.00
-+
Reactivity: H,M,R    
Applications: WB    
Host Species: Rabbit    
Clonality: Polyclonal    
Gene Name:

AP-4 complex subunit mu-1

Synonyms:

AP 4 complex subunit mu 1, AP4M1, MU 4, Mu adaptin related protein 2, MU ARP2, Mu subunit of AP 4, mu4

Immunogen:

Recombinant protein corresponding to Mouse AP4M1

Uniprot ID:

Q9JKC7

Isotype:

IgG

Purity:

Affinity purification

Predicted MW. / Observed MW.

50 kDa / 55 kDa




Product Usage Information

WB

Human, Mouse, Rat

1: 2000-1: 4000

lung, testis




Background

Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system (By similarity). It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asymmetric localization of somatodendritic proteins in neurons . Within AP-4, the mu-type subunit AP4M1 is directly involved in the recognition and binding of tyrosine-based sorting signals found in the cytoplasmic part of cargos. The adaptor protein complex 4 (AP-4) may also recognize other types of sorting signal (By similarity.




Images

Picture 10(27).png

Western blot analysis of AP4M1 (GB114461) at dilution of 1: 2000




Storage

StorageStore at -20°C for one year. Avoid repeated freeze/thaw cycles.
Storage BufferPBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


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