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Anti-AQP11 Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Aquaporin-11 |
Synonyms: | AQP-11 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse AQP11 |
Uniprot ID: | Q8BHH1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 30 kDa / 35 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 500-1: 1000 | heart |
Background
Channel protein that facilitates the transport of water, glycerol and hydrogen peroxide across membrane of cell or organelles guaranteeing intracellular homeostasis in several organes like liver, kidney and brain . In situation of stress, participates in endoplasmic reticulum (ER) homeostasis by regulating redox homeostasis through the transport of hydrogen peroxide across the endoplasmic reticulum membrane thereby regulating the oxidative stress through the NADPH oxidase 2 pathway . Plays a role by maintaining an environment suitable for translation or protein foldings in the ER lumen namely by participating in the PKD1 glycosylation processing resulting in regulation of PKD1 membrane trafficking thereby preventing the accumulation of unfolding protein in ER .
Images
| Western blot analysis of AQP11 (GB114710) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
