Reactivity: | M,R |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | ATP6V1C2 rabbit polyclonal antibody |
Gene Name: | V-type proton ATPase subunit C 2 |
Synonyms: | V-ATPase subunit C 2, Vacuolar proton pump subunit C 2, Atp6v1c2, Atp6c2, Vacuolar H+ ATPase C2, VMA 5, Vacuolar proton pump subunit C 2, V type proton ATPase subunit C 2 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse ATP6V1C2 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm |
Uniprot ID: | Q99L60, Q6AYE4 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 100-1: 800 | lung, lung+LPS, pneumonia |
Background
ATP6V1C2 encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. This gene encodes alternate transcriptional splice variants, encoding different V1 domain C subunit isoforms.
Images
Immunohistochemistry of paraffin embedded mouse pneumonia using B3GALT4 (GB111599) at dilution of 1:400 (300x lens) |
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Immunofluorescence of paraffin embedded mouse lung using ATP6V1C2 (GB111599) at dilution of 1:200 (200x lens) | |
Immunofluorescence of paraffin embedded rat lung+LPS using ATP6V1C2 (GB111599) at dilution of 1:200 (200x lens) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |