Reactivity: | H,M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | AVPR1B rabbit polyclonal |
Gene Name: | Vasopressin V1b receptor |
Synonyms: | V1bR, AVPR V1b, VPR V3, Antidiuretic hormone receptor 1b, Vasopressin V3 receptor, Avpr1b, AVPR3, Vasopressin V1b receptor, VPR3 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse AVPR1B |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 47 kDa |
Observed MW. | 50 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 2000-1: 4000 | Lung, liver, pancreas, kidney, brain, cerebellum |
Background
The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. A spliced antisense transcript of this gene has been reported but its function is not known.
Images
Western blot analysis of AVPR1B (GB112997) at dilution of 1: 4000 | |
Western blot analysis of AVPR1B (GB112997) at dilution of 1: 4000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |