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Anti-Abi-1 Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | TSP50 rabbit polyclonal |
Gene Name: | Probable threonine protease PRSS50 |
Synonyms: | Cancer/testis antigen 20, CT20, PRSS50, Serine protease 50, Testis-specific protease-like protein 50, TSP50 |
Immunogen: | Recombinant protein corresponding to Mouse TSP50 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 49 kDa |
Observed MW. | 45 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 2000-1: 4000 | brain, kidney, testis |
Background
TSP50 (Testis-specific protease-like protein 50) is also named as PRSS50, CT20 and belongs to the peptidase S1 family. It can enhance the expression of NFKB target genes involved in cell proliferation, and promotes cell proliferation, at least partially, through activation of the NFKB signalling pathway. There are two protein bands of 37 kDa and 43 kDa to be detected in human testes that the the difference is most likely caused by posttranslational proteolytic cleavage. The full length protein has a signal peptide with 39 amino acids and two glycosylation sites.
Images
 | Western blot analysis of TSP50 (GB113646) at dilution of 1: 4000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
