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Anti-Adiponectin Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Adiponectin |
Synonyms: | ACDC, ACRP30, adiponectin, ADIPOQ, ADIPQTL1, ADPN, APM 1, APM1, GBP28, Gelatin binding protein |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Adiponectin |
Uniprot ID: | Q60994 |
Isotype: | lgG |
Purity: | Affinity purification |
Subcellular location: | Secreted |
Product Usage Information
IHC/IF | Mouse, Rat | 1: 100-1: 200 | brown fat |
Background
Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW.
Images
| Immunohistochemistry analysis of paraffin embedded mouse Brown fat using Adiponectin (GB115581) at dilution of 1: 150 |
| Immunohistochemistry analysis of paraffin embedded rat Brown fat using Adiponectin (GB115581) at dilution of 1: 150 |
| Immunohistochemistry analysis of paraffin embedded rat Brown fat using Adiponectin (GB115581) at dilution of 1: 150 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
