Your shopping cart is empty!
Anti-Alpha B Crystallin Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Alpha B Crystallin rabbit polyclonal antibody |
Gene Name: | Alpha-crystallin B chain |
Synonyms: | Alpha(B)-crystallin, P23, Cryab, Crya2, AACRYA, Crystallin alpha B, Crystallin alpha polypeptide 2, CTPP2, HspB5, Heat shock protein beta 5 |
Immunogen: | Recombinant protein corresponding to Mouse Alpha B Crystallin |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 20 kDa |
Observed MW. | 20 kDa |
Uniprot ID: | P23927, P23928 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 500-1: 1000 | heart |
Background
Alpha B-crystallin, encoded by CRYAB gene, is multifunctional, serving as both a major structural protein in the lens and a small heat-shock protein in other tissues in mammals. Alpha B-crystallin may contribute to the transparency and refractive index of the lens. Single nucleotide polymorphisms (SNPs) in the promoter region of CRYAB gene have been associated with in multiple sclerosis. Mutations in the CRYAB gene cause distinct clinical phenotypes including isolated posterior polar cataract, myofibrillar myopathy, cardiomyopathy, or a multisystemic disorder combining all these features.
Images
| Western blot analysis of Cryab (GB111912) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
