Reactivity: | H |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | Androgen receptor |
Synonyms: | Dihydrotestosterone receptor, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM, Androgen receptor, AIS, AR, DHTR |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Human Androgen receptor |
Uniprot ID: | P10275 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 99 kDa / 110 kDa |
Product Usage Information
WB | Human | 1: 500-1: 1000 | LNCaP |
Background
Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins. Transcription activation is down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3.Isoform 3 and isoform 4 lack the C-terminal ligand-binding domain and may therefore constitutively activate the transcription of a specific set of genes independently of steroid hormones.
Images
Western blot analysis of AR (GB115311) at dilution of 1:1000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |