Reactivity: | H,M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | Angiotensin Converting Enzyme 1 rabbit polyclonal |
Gene Name: | Angiotensin-converting enzyme |
Synonyms: | ACE1, DCP, DCP1, CD143, Kininase II, ACE |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse ACE |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Secreted, Cell membrane, Cytoplasm |
Uniprot ID: | P09470, P47820 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Mouse, Rat | 1: 500-1: 1000 | testis |
IF | Mouse, Rat | 1: 500-1: 1000 | testis |
Background
Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI-anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety.
Images
Immunohistochemistry analysis of paraffin-embedded mouse testis using ACE (GB11257) at dilution of 1: 1000 |
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Immunohistochemistry analysis of paraffin-embedded Rat testis using ACE (GB11257) at dilution of 1: 500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |