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Anti-Angiotensin Converting Enzyme 1 Rabbit pAb (100 μl)
| Reactivity: | M,R & H,M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Angiotensin-converting enzyme |
Synonyms: | ACE, ACE1, Angiotensin converting enzyme, CD143, DCP, DCP1, Dipeptidyl carboxypeptidase I, Kininase II, MVCD3 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse ACE |
Uniprot ID: | P09470 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Secreted, Cell membrane, Cytoplasm Note=Detected in both cell membrane and cytoplasm in neurons. |
Predicted MW. / Observed MW. | 151,84 kDa / 180 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 500-1: 1000 | lung |
IHC/IF | Human, Mouse, Rat | 1: 400-1: 1200 | kidney, lung, lung cancer |
Background
Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI-anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety. This GPIase activity seems to be crucial for the egg-binding ability of the sperm.
Images
| Western blot analysis of ACE (GB115439) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded human lung cancer using ACE (GB115439) at dilution of 1: 400 |
| Immunohistochemistry analysis of paraffin embedded mouse kidney using ACE (GB115439) at dilution of 1: 400 |
| Immunohistochemistry analysis of paraffin embedded mouse lung using ACE (GB115439) at dilution of 1: 400 |
| Immunohistochemistry analysis of paraffin embedded rat lung using ACE (GB115439) at dilution of 1: 400 |
| Immunohistochemistry analysis of paraffin embedded rat kidney using ACE (GB115439) at dilution of 1: 400 |
| Immunohistochemistry analysis of paraffin embedded human kidney using ACE (GB115439) at dilution of 1: 400 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
