Reactivity: | M & H,M,R & H,M,R |
Applications: | WB & IHC & IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | Angiotensin Converting Enzyme 2 rabbit polyclonal |
Gene Name: | Angiotensin-converting enzyme 2 |
Synonyms: | ACE-related carboxypeptidase, Ace2, ACEH, Processed angiotensin-converting enzyme 2 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Angiotensin Converting Enzyme 2 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Predicted MW. | 92 kDa |
Observed MW. | 110 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse | 1: 250-1: 500 | intestine |
IHC | Human, Mouse, Rat | 1: 700-1: 1400 | small intestine, ileum, duodenum |
IF | Human, Mouse, Rat | 1: 700-1: 1400 | testis, duodenum, lung, jejunum |
Background
Angiotensin converting enzyme 2 (ACE2) is an exopeptidase that catalyses the conversion of angiotensin I to the nonapeptide angiotensin[1-9], or the conversion of angiotensin II to angiotensin 1-7. ACE2 has direct effects on cardiac function,a and is expressed predominantly in vascular endothelial cells of the heart and the kidneys. ACE2 is not sensitive to the ACE inhibitor drugs used to treat hypertension.
Images
Western blot analysis of ACE2 (GB112047) at dilution of 1: 500 Lane 1: Mouse intestine tissue lysate | |
Immunohistochemistry analysis of paraffin-embedded human small intestine using ACE2 (GB112047) at dilution of 1: 1400 | |
Immunohistochemistry analysis of paraffin-embedded mouse ileum using ACE2 (GB112047) at dilution of 1: 1400 | |
Immunohistochemistry analysis of paraffin-embedded rat ileum using ACE2 (GB112047) at dilution of 1: 1400 | |
Immunohistochemistry analysis of paraffin-embedded mouse duodenum using ACE2 (GB112047) at dilution of 1: 1400 | |
Immunofluorescent analysis of paraformaldehyde-fixed mouse testis using ACE2 (GB112047) at dilution of 1: 1400 | |
Immunofluorescent analysis of paraformaldehyde-fixed mouse duodenum using ACE2 (GB112047) at dilution of 1: 1400 | |
Immunofluorescent analysis of paraformaldehyde-fixed rat lung using ACE2 (GB112047) at dilution of 1: 1400 | |
Immunofluorescent analysis of paraformaldehyde-fixed rat jejunum using ACE2 (GB112047) at dilution of 1: 1400 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |