Reactivity: | H,M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | Annexin-11 rabbit polyclonal antibody |
Gene Name: | Annexin A11 |
Synonyms: | Annexin XI, Annexin-11, CAP-50, Anx11, Calcyclin-associated annexin 50, Anxa11 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Annexin-11 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 54 kDa |
Observed MW. | 54 kDa |
Uniprot ID: | P50995, P97384, Q5XI77 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | liver, skeletal muscle, uterus |
Background
This gene encodes a member of the annexin family, a group of calcium-dependent phospholipid-binding proteins. Annexins have unique N-terminal domains and conserved C-terminal domains, which contain the calcium-dependent phospholipid-binding sites. It is characterized by a conserved core domain, which binds to phospholipids in a Ca2+ dependent manner, and a unique amino terminal region, which may confer binding specificity. The annexin family has been implicated as regulators of such diverse processes as ion-flux, endocytosis and exocytosis, and cellular adhesion. Two forms of Annexin XI, designated A and B, have been identified. Transfection of COS-7 cells with Annexin XI-A, but not Annexin XI-B, causes formation of Annexin XI-associated vesicles.
Images
Western blot analysis of Annexin-A11 (GB11951) at dilution of 1: 500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |