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Anti-Annexin-4/ANXA4 Rabbit pAb (100 μl)
| Reactivity: | H,M,R & M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Annexin-4 rabbit polyclonal antibody |
Gene Name: | Annexin A4 |
Synonyms: | Annexin IV, Annexin-4, Anxa4, Anx4 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Annexin-4 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus, Secreted, Cell Membrane |
Predicted MW. | 36 kDa |
Observed MW. | 36 kDa |
Uniprot ID: | P09525, P97429, P55260 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1:500-1:1000 | heart, liver |
IHC/IF | Mouse, Rat | 1:1500-1:3000 | colon, placenta, small intestine, uterus |
Background
The Annexins are a family of structurally similar proteins. Annexins bind to phospholipids and may be involved in regulation of membrane transport, membrane channel activity, and interaction of the cell membrane with the extracellular matrix. Annexin A4 belongs to the annexin family of calcium dependent phospholipid binding proteins. Although their functions are still not clearly defined, several members of the annexin family have been implicated in membrane related events along exocytotic and endocytotic pathways. Isolated from human placenta, ANXA4 encodes a protein that has possible interactions with ATP, and has in vitro anticoagulant activity and also inhibits phospholipase A2 activity. ANXA4 is almost exclusively expressed in epithelial cells.
Images
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Western blot analysis of Annexin-A4 (GB111147) at dilution of 1: 500 |
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Immunohistochemistry of paraffin embedded mouse small intestine using Annexin-A4 (GB111147) at dilution of 1: 1800 (400x lens) |
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Immunohistochemistry of paraffin embedded rat placenta using Annexin-A4 (GB111147) at dilution of 1: 1800 (400x lens) |
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Immunohistochemistry of paraffin embedded rat small intestine using Annexin-A4 (GB111147) at dilution of 1: 1800 (400x lens) |
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Immunofluorescence of paraffin embedded mouse colon using Annexin-A4 (GB111147) at dilution of 1: 1800 (400x lens) |
 | Immunofluorescence of paraffin embedded mouse small intestine using Annexin-A4 (GB111147) at dilution of 1: 1800 (400x lens) |
| Immunofluorescence of paraffin embedded rat placenta using Annexin-A4 (GB111147) at dilution of 1: 1800 (400x lens) |
 | Immunofluorescence of paraffin embedded rat small intestine using Annexin-A4 (GB111147) at dilution of 1: 1800 (400x lens) |
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Immunofluorescence of paraffin embedded rat uterus using Annexin-A4 (GB111147) at dilution of 1: 1800 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
