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Anti-Annexin A1/ANXA1 Rabbit pAb (100 μl)
| Reactivity: | H,M,R & H,M,R |
| Applications: | WB & IHC |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Annexin A1/ANXA1 rabbit polyclonal |
Gene Name: | Annexin A1 |
Synonyms: | Annexin 1, Annexin I, ANX1, ANXA1, Calpactin 2, Calpactin II, Chromobindin 9, Lipocortin I, LPC1 |
Immunogen: | Recombinant protein corresponding to Mouse Annexin A1/ANXA1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus, Cell membrane, Endosome |
Predicted MW. | 39 kDa |
Observed MW. | 34 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 1000-1: 2000 | placenta, lung |
IHC | Human, Mouse, Rat | 1: 3000-1: 6000 | lung, spleen |
Background
This gene encodes a protein that belongs to a family of Ca(2+) dependent phospholipid binding proteins which have a molecular weight of approximately 35,000 to 40,000 and are preferentially located on the cytosolic face of the plasma membrane. Annexin I protein has an apparent relative molecular mass of 40 kDa, with phospholipase A2 inhibitory activity. Since phospholipase A2 is required for the biosynthesis of the potent mediators of inflammation, prostaglandins and leukotrienes, annexin I may have potential anti inflammatory activity.
Images
| Western blot analysis of ANXA1 (GB113305) at dilution of 1: 2000 |
| Immunohistochemistry analysis of paraffin-embedded mouse lung using ANXA1 (GB113305) at dilution of 1: 6000 |
| Immunohistochemistry analysis of paraffin-embedded rat lung using ANXA1 (GB113305) at dilution of 1: 6000 |
| Immunohistochemistry analysis of paraffin-embedded mouse spleen using ANXA1 (GB113305) at dilution of 1: 6000 |
| Immunohistochemistry analysis of paraffin-embedded rat spleen using ANXA1 (GB113305) at dilution of 1: 6000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
