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Anti-Caveolin-1 Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Caveolin-1 |
Synonyms: | CAV1, BSCL3, CGL3, LCCNS, MSTP085, PPH3, VIP21, Caveolin 1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Caveolin-1 |
Uniprot ID: | |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane, Golgi apparatus, Caveola, Peripheral membrane protein |
Predicted MW. / Observed MW. | 20 kDa / 20 kDa |
Product Usage Information
WB | Human, Mouse, Rat | 1: 800-1: 1000 | heart, lung, skin |
IHC/IF | Mouse, Rat | 1: 1000-1: 3000 | lung, kidney |
Background
The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 MAP kinase cascade. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex.
Images
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Western blot analysis of Caveolin-1 (GB11409) at dilution of 1:800. |
| Immunohistochemistry analysis of paraffin-embedded rat kidney using Caveolin-1 (GB11409) at dilution of 1:1000 |
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Immunohistochemistry analysis of paraffin-embedded mouse lung using Caveolin-1 (GB11409) at dilution of 1:1500 |
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Immunohistochemistry analysis of paraffin-embedded rat kidney using Caveolin-1 (GB11409) at dilution of 1:1500 |
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Immunofluorescence analysis of paraffin-embedded mouse kidney using Caveolin-1 (GB11409) at dilution of 1:1000 |
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Immunofluorescence analysis of paraffin-embedded mouse testis using Caveolin-1 (GB11409) at dilution of 1:1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
