Reactivity: | M,R |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | Apolipoprotein A II/ApoA-II rabbit polyclonal antibody |
Gene Name: | Apolipoprotein A-II |
Synonyms: | Apo-AII, ApoA-II, Apolipoprotein A2, ProapoA-II, Apoa2, Proapolipoprotein A-II |
Immunogen: | Recombinant protein corresponding to Mouse Apolipoprotein A II |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Secreted |
Uniprot ID: | P09813 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 400-1: 1300 | liver |
Background
Apolipoprotein A II is the second most abundant protein of the high density lipoprotein particles. The apolipoprotein A II gene consists of 4 exons and 3 introns. The four exons encode the 5' untranslated region, pre peptide, a short N terminal domain and a C terminal domain composed of a variable number of lipid binding amphipathic helices. Familial apolipoprotein A II deficiency may result from a splice junction alteration which blocks splicing of intron 3 from the primary transcript and result in the formation of a non functional mRNA.
Images
Immunohistochemistry of paraffin embedded mouse liver using ApoA2 (GB112078) at dilution of 1:650 (300x lens) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |