Reactivity: | M,R & M,R |
Applications: | WB & IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | Apolipoprotein A I rabbit polyclonal antibody |
Gene Name: | Apolipoprotein A-I |
Synonyms: | Apo-AI, ApoA-I, Apolipoprotein A1, ProapoA-I, Apoa1, Lvtw1, Brp14, Sep1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Human Apolipoprotein A I |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Secreted |
Predicted MW. | 31 kDa |
Observed MW. | 24 kDa |
Uniprot ID: | Q00623, P04639 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Mouse, Rat | 1: 500-1: 1000 | kidney, testis, plasma |
IHC/IF | Mouse, Rat | 1: 300-1: 1800 | duodenum, kidney, liver, testis |
Background
This gene encodes apolipoprotein A-I, which is the major protein component of high density lipoprotein (HDL) in plasma. The protein promotes cholesterol efflux from tissues to the liver for excretion, and it is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. This gene is closely linked with two other apolipoprotein genes on chromosome 11. Defects in this gene are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis.
Images
Western blot analysis of Apoa1 (GB112379) at dilution of 1: 500 | |
Immunohistochemistry of paraffin embedded mouse duodenum using Apoa1 (GB112379) at dilution of 1: 300 (400x lens) | |
Immunohistochemistry of paraffin embedded mouse liver using Apoa1 (GB112379) at dilution of 1: 300 (400x lens) | |
Immunohistochemistry of paraffin embedded rat liver using Apoa1 (GB112379) at dilution of 1: 300 (400x lens) | |
Immunofluorescence of paraffin embedded mouse kidney using Apoa1 (GB112379) at dilution of 1: 300 (400x lens) | |
Immunofluorescence of paraffin embedded mouse testis using Apoa1 (GB112379) at dilution of 1: 300 (400x lens) | |
Immunofluorescence of paraffin embedded rat kidney using Apoa1 (GB112379) at dilution of 1: 300 (400x lens) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |