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Anti-Apolipoprotein E Rabbit pAb (100 μl)
| Reactivity: | M,R & M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Apolipoprotein E rabbit polyclonal antibody |
Gene Name: | Apolipoprotein E |
Synonyms: | Apo-E, Apoe, Apolipoprotein E precursor, AD2, Alzheimer disease 2, APOEA, Apolipoprotein E2, ApoE2 |
Immunogen: | Recombinant protein corresponding to Mouse Apolipoprotein E |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Secreted |
Predicted MW. | 36 kDa |
Observed MW. | 34 kDa |
Uniprot ID: | P02649, P08226, P02650 |
Product Usage Information
WB | Mouse, Rat | 1: 500-1: 1000 | brain, liver, spleen |
IHC/IF | Mouse, Rat | 1: 500-1: 1600 | kidney, liver, lung |
Background
Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. ApoE exists in three major isoforms; E2, E3, and E4, which differ from one another by a single amino-acid substitution. Compared with E3 and E4, E2 exhibits the lowest receptor binding affinity.
Images
| Western blot analysis of APOE2 (GB112288) at dilution of 1: 500 |
| Western blot analysis of APOE2 (GB112288) at dilution of 1: 500 |
| Immunohistochemistry of paraffin embedded mouse kidney using APOE2 (GB112288) at dilution of 1: 500 (400x lens) |
| Immunohistochemistry of paraffin embedded mouse liver using APOE2 (GB112288) at dilution of 1: 500 (400x lens) |
| Immunohistochemistry of paraffin embedded rat kidney using APOE2 (GB112288) at dilution of 1: 500 (400x lens) |
| Immunohistochemistry of paraffin embedded rat liver using APOE2 (GB112288) at dilution of 1: 500 (400x lens) |
| Immunofluorescence of paraffin embedded mouse liver using APOE2 (GB112288) at dilution of 1: 650 (400x lens) |
| Immunofluorescence of paraffin embedded mouse spleen using APOE2 (GB112288) at dilution of 1: 650 (400x lens) |
 | Immunofluorescence of paraffin embedded rat kidney using APOE2 (GB112288) at dilution of 1: 650 (400x lens) |
| Immunofluorescence of paraffin embedded rat liver using APOE2 (GB112288) at dilution of 1: 650 (400x lens) |
| Immunofluorescence of paraffin embedded rat lung using APOE2 (GB112288) at dilution of 1: 650 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
