Reactivity: | M,R |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | Aspartate Aminotransferase rabbit polyclonal |
Gene Name: | Aspartate aminotransferase, cytoplasmic |
Synonyms: | AATC, CAT, GIG18, GOT1, Transaminase A, cCAT, Glutamate oxaloacetate transaminase 1, cAspAT |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Aspartate Aminotransferase |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 46 kDa |
Observed MW. | 46 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 1000-1: 2000 | heart, liver |
IHC | Rat | 1: 2000-1: 4000 | brain |
Background
Glutamate oxaloacetate transaminase 1 (GOT1) catalyzes the reversible reaction of L-aspartate and alpha-ketoglutarate into oxaloacetate and L-glutamate and plays a key role in carbon and nitrogen metabolism. GOT1 can potentially control the intracellular levels of reactive oxygen species (ROS) through NADPH synthesis and enhances tumor growth. GOT1 expression correlates with the growth of several tumors.
Images
Western blot analysis of GOT1 (GB113401) at dilution of 1: 2000 | |
Immunohistochemistry analysis of paraffin-embedded rat brain using GOT1 (GB113401) at dilution of 1: 4000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |