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Anti-B3GAT1 Rabbit pAb (100 μl)
| Reactivity: | H |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 |
Synonyms: | B3GAT1, CD57, GlcAT-P, GLCATP, GlcUAT-P, Glucuronosyltransferase P, HNK-1, HNK1, LEU7, NK 1 |
Immunogen: | KLH conjugated Synthetic peptidecorresponding to Mouse B3GAT1 |
Uniprot ID: | Q9CW73 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Endoplasmic reticulum, Golgi apparatus, Secreted |
Product Usage Information
IHC/IF | Human | 1: 600-1: 1200 | tonsil |
Background
B3GAT1 plays a key role in neurodevelopment.B3GAT1 Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins. Can also play a role in glycosaminoglycan biosynthesis. Substrates include asialo-orosomucoid (ASOR), asialo-fetuin, and asialo-neural cell adhesion molecule. Requires sphingomyelin for activity: stearoyl-sphingomyelin was the most effective, followed by palmitoyl-sphingomyelin and lignoceroyl-sphingomyelin. Activity was demonstrated only for sphingomyelin with a saturated fatty acid and not for that with an unsaturated fatty acid, regardless of the length of the acyl group.
Images
 | Immunohistochemistry analysis of paraffin-embedded human tonsil using B3GAT1 (GB113461) at dilution of 1: 1200 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
