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| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | BAD rabbit polyclonal |
Gene Name: | Bcl2-associated agonist of cell death |
Synonyms: | BAD, BBC2, BBC6, Bcl-2-binding component 6, Bcl-2-like protein 8, Bcl2-L-8, BCL2L8, Bcl2 antagonist of cell death |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Human BAD |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 23 kDa |
Observed MW. | 23-26 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | brain, glioma |
Background
BAD, also named as BBC6 and BCL2L8, promotes cell death. It is successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. BAD can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2. It appears to act as a link between growth factor receptor signaling and the apoptotic pathways.
Images
 | Western blot analysis of BAD (GB113746) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
