Reactivity: | H,R & H,M,R |
Applications: | WB & IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 |
Synonyms: | BRG1-associated factor 57, BAF57, Smarce1, Chromatin remodeling complex BRG1 associated factor 57 |
Immunogen: | Recombinant protein corresponding to Mouse SMARCE1 |
Uniprot ID: | O54941 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus |
Predicted MW. / Observed MW. | 47 kDa / 55 kDa |
Product Usage Information
WB | Human, Rat | 1: 500-1: 1000 | lung |
IHC/IF | Human, Mouse, Rat | 1: 500-1: 1000 | brain, colon, hippocampus |
Background
Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state.
Images
Western blot analysis of SMARCE1 (GB112084) at dilution of 1: 1000 | |
Immunohistochemistry analysis of paraffin embedded rat colon using SMARCE1 (GB112084) at dilution of 1: 500 | |
Immunofluorescence analysis of paraffin embedded rat hippocampus using SMARCE1 (GB112084) at dilution of 1: 500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |