Reactivity: | H,M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | BCAS3 rabbit polyclonal antibody |
Gene Name: | Breast carcinoma-amplified sequence 3 homolog |
Synonyms: | K20D4, Protein rudhira, AU021018, BC028339, rudhira, MGC4973, Maab1 protein, MAAB, GAOB1, FLJ20128 |
Immunogen: | Recombinantproteincorrespondingto Mouse BCAS3 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 101 kDa |
Observed MW. | 120 kDa |
Uniprot ID: | Q9H6U6, Q8CCN5 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | brain, hippocampus |
Background
Rudhira/BCAS3 (Breast Cancer Amplified Sequence 3) is a conserved protein expressed in the embryonic vasculature and malignant tumors. Rudhira is a predicted WD40 domain protein. During mouse development Rudhira is expressed in erythropoietic and angiogenic precursors but not in their differentiated progeny. This transient expression of Rudhira is also seen in normal adult angiogenesis. BCAS3, the human ortholog of Rudhira is 98% identical and the gene maps to a breakpoint of hematological neoplasms on chromosome 17q23.1. BCAS3 is also expressed in vascular development in embryoid bodies in vitro and was originally identified as a gene over-expressed in breast cancers.
Images
Western blot analysis of BCAS3 (GB111646) at dilution of 1: 500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |