Your shopping cart is empty!
Anti-BMPR1B Rabbit pAb (100 μl)
| Reactivity: | H,M |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Bone morphogenetic protein receptor type-1B |
Synonyms: | BMPR-IB, Activin receptor like kinase 6, Acvrlk6, ALK6, alk6tr, BMP type-1B receptor, BMPR IB, BMPR-1B, Bmpr1b, BMPRIB, BR1b, CDw293, CDw293 antigen, CFK43a, zALK6 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse BMPR1B |
Uniprot ID: | P36898 |
Isotype: | lgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 57 kDa / 57 kDa |
Product Usage Information
WB | Human, Mouse | 1: 300-1: 400 | HeLa, NIH/3T3 |
Background
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP7/OP-1. Receptor for GDF5. Positively regulates chondrocyte differentiation through GDF5 interaction.
Images
| WB analysis of BMPR1B (GB115499). Sample: Protein treated by RIPA Lysis Buffer (G2002). Blocking buffer: 3% Nonfat dry milk (GC310001) in TBST, RT, 1h. Primary antibody: 1: 300, 4°C overnight. Secondary antibody: HRP Goat Anti-Rabbit lgG (GB23303), 1: 3000, RT, 1h. |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
