Reactivity: | H |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | CA9 rabbit polyclonal antibody |
Gene Name: | Carbonic anhydrase 9 |
Synonyms: | Carbonate dehydratase IX, CA-IX, MN, G250, Carbonic anhydrase IX, Membrane antigen MN, P54/58N, RCC-associated antigen G250, CA9, pMW1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Human CA9 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell Membrane, Nucleus |
Uniprot ID: | Q16790 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human | 1: 700-1: 2000 | colon cancer, gastric cancer, stomach |
Background
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and the only tumor-associated carbonic anhydrase isoenzyme known.
Images
Immunohistochemistry of paraffin embedded human colon cancer using CA9 (GB111184) at dilution of 1:700 (400x lens) |
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Immunohistochemistry of paraffin embedded human stomach using CA9 (GB111184) at dilution of 1:700 (400x lens) |
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Immunofluorescence of paraffin embedded human gastric cancer using CA9 (GB111184) at dilution of 1:1400 (400x lens) |
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Immunofluorescence of paraffin embedded human stomach using CA9 (GB111184) at dilution of 1:1400 (400x lens) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |