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Anti-CADPS Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Calcium-dependent secretion activator 1 |
Synonyms: | CADPS, CADPS1, CAPS, CAPS 1, CAPS1, KIAA1121 |
Immunogen: | Recombinant protein corresponding to Mouse CAPS1 |
Uniprot ID: | Q80TJ1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 153 kDa / 150 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 1000-1: 2000 | brain,pancreas |
Background
Calcium-binding protein involved in exocytosis of vesicles filled with neurotransmitters and neuropeptides.Probably acts upstream of fusion in the biogenesis or maintenance of mature secretory vesicles.Regulates catecholamine loading of DCVs.May specifically mediate the Ca(2+)-dependent exocytosis of large dense-core vesicles (DCVs) and other dense-core vesicles by acting as a PtdIns(4,5)P2-binding protein that acts at prefusion step following ATP-dependent priming and participates in DCVs-membrane fusion.However, it may also participate in small clear synaptic vesicles (SVs) exocytosis and it is unclear whether its function is related to Ca(2+) triggering.
Images
| WB analysis of CAPS1(GB115626). |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
