Reactivity: | H,M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | HP1 gamma/CBX3 rabbit polyclonal antibody |
Gene Name: | Chromobox protein homolog 3 |
Synonyms: | Heterochromatin protein 1 homolog gamma, HP1 gamma, M32, Modifier 2 protein, Cbx3, HECH, HP1Hs gamma |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse HP1 gamma/CBX3 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 21 kDa |
Observed MW. | 21 kDa |
Uniprot ID: | Q13185, P23198 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | testis, liver, colon |
Background
The family of Heterochromatin protein 1 (HP1) proteins is a family of highly conserved heterochromatin-associated non-histone chromosomal proteins , which has important functions in nucleus. These functions include gene activation or repression, regulation of binding of cohesion complexes to centromere, sequestration of genes to nuclear periphery, and heterochromatin formation and propagation. Much evidence shows that HP1 proteins interact with numerous proteins including methylated histones, histone methyltransferases and so on. CBX3 is one of the paralogues of HP1 proteins.
Images
Western blot analysis of CBX3 (GB111730) at dilution of 1: 500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |