Reactivity: | M,R & M,R |
Applications: | WB & IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | CD133 rabbit polyclonal antibody |
Gene Name: | Prominin-1 |
Synonyms: | AC133, Antigen AC133, CD133, CORD12, MCDR2, MSTP061, PROM1, Prominin like protein 1, PROML1, RP41, STGD4, STGD4, Hematopoietic stem cell antigen |
Immunogen: | Recombinant protein corresponding to Mouse CD133 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane, Cell projection, Endoplasmic reticulum |
Predicted MW. | 97 kDa |
Observed MW. | 130 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Mouse, Rat | 1: 500-1: 1000 | kidney, heart, fetal kidney, embryonic rat |
IHC/IF | Mouse, Rat | 1: 700-1: 1400 | embryonic intestines, embryonic pancreas, embryonic eye, embryonic lung |
Background
CD133, also known as PROM1 (prominin-1) or AC133, belongs to the prominin family. CD133 is a transmembrane glycoprotein with an NH2-terminal extracellular domain, five transmembrane loops and a cytoplasmic tail. The expression of CD133 has been reported in hematopoietic stem cells, endothelial progenitor cells, neuronal and glial stem cells, suggesting the potential role of CD133 as a cell surface marker of adult stem cells. CD133 has also been reported as a marker of cancer stem cells in various human tumors.
Images
Western blot analysis of CD133 (GB113807) at dilution of 1: 1000 | |
Immunohistochemistry analysis of paraffin-embedded mouse embryonic intestines using CD133 (GB113807) at dilution of 1: 1400 | |
Immunohistochemistry analysis of paraffin-embedded mouse embryonic pancreas using CD133 (GB113807) at dilution of 1: 1400 | |
Immunohistochemistry analysis of paraffin-embedded rat embryonic eye using CD133 (GB113807) at dilution of 1: 1400 | |
Immunohistochemistry analysis of paraffin-embedded rat embryonic lung using CD133 (GB113807) at dilution of 1: 1400 | |
Immunohistochemistry analysis of paraffin-embedded rat placenta using CD133 (GB113807) at dilution of 1: 1400 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |