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| Reactivity: | H & H |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | CD16 rabbit polyclonal antibody |
Gene Name: | Fc fragment of IgG, low affinity IIIa, receptor (CD16a) |
Synonyms: | CD16, CD16A, CD16a antigen, Fc gamma RIII, Fc gamma RIII alpha, Fc gamma RIIIa, FCG3, FCGR3, FCGR3A, FCGRIII, FCR 10, FCRIII, FCRIIIA, IGFR3, IgG Fc receptor III 2 |
Immunogen: | Recombinant protein corresponding to Human CD16 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane |
Predicted MW. | 26 kDa |
Observed MW. | 50-70 kDa |
Uniprot ID: | O75015 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human | 1: 500-1: 1000 | liver cancer |
IHC/IF | Human | 1: 2000-1: 4000 | liver, esophageal cancer, ovarian cancer |
Background
CD16 is a 50-70-kDa low affinity Fc receptor found on the surface of natural killer cells, neutrophil polymorphonuclear leukocytes, monocytes and macrophages. CD16 mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis. CD16 has been identified as Fc receptors FcγRIIIa (CD16a) and FcγRIIIb (CD16b), encoded by two nearly identical genes, FCGR3A and the FCGR3B.
Images
 | Western blot analysis of CD16 (GB113963) at dilution of 1: 1000 |
 | Immunohistochemistry of paraffin embedded human liver using CD16 (GB113963) at dilution of 1: 1400 (200x lens) |
 | Immunohistochemistry of paraffin embedded human esophageal cancer using CD16 (GB113963) at dilution of 1: 1400 (200x lens) |
 | Immunohistochemistry of paraffin embedded human ovarian cancer using CD16 (GB113963) at dilution of 1: 1400 (200x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
