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Anti-CD276 Rabbit pAb (100 μl)
| Reactivity: | H |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | CD276 rabbit polyclonal antibody |
Gene Name: | CD276 antigen |
Synonyms: | B7 homolog 3, B7-H3, Costimulatory molecule, CD276, B7h3, 4Ig B7 H3 |
Immunogen: | Recombinant protein corresponding to Mouse CD276 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 34 kDa |
Observed MW. | 100 kDa |
Uniprot ID: | Q5ZPR3 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human | 1: 500-1: 1000 | HeLa, HepG2, A-431, MCF-7, 293T, U-251MG, Jurkat, U-2OS, Raji |
Background
B7-H3 (CD276) is a type I transmembrane protein expressed on many tissues and cell types. B7-H3 is a 100-kDa glycoprotein that belongs to the B7 immunoregulatory family and participates in the regulation of T-cell-mediated immune response probably by functioning as both a T cell costimulator and coinhibitor Overexpressed on a wide range of human solid cancers, B7-H3 has been implicated in cancer progression and metastasis and becomes an attractive target for cancer immunotherapy.
Images
| Western blot analysis of CD276 (GB111975) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
