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| Reactivity: | M,R & M,R |
| Applications: | IHC & IF |
| Host Species: | |
| Clonality: | |
| Full Name: |
CD31 goat polyclonal |
| Gene Name: |
Platelet endothelial cell adhesion molecule |
|
Synonyms: |
CD31 Antigen, EndoCAM, PECAM-1, GPIIA, PECA1 |
| Immunogen: |
Recombinant protein corresponding to mouse CD31 |
| Isotype: | IgG |
| Purity: | Affinity purification |
| Subcellular location: |
Membrane, Cell junction |
| Uniprot ID: | Q08481, Q3SWT0 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Mouse, Rat | 1:50-1:200 | Liver,heart,tumor |
IF | Mouse, Rat | 1:50-1:100 | Liver,heart,tumor |
Background
Platelet endothelial cell adhesion molecule (PECAM-1) also known as cluster of differentiation 31 (CD31) is a protein that in humans is encoded by the PECAM1 gene found on chromosome 17. PECAM-1 plays a key role in removing aged neutrophils from the body. PECAM-1 is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. The encoded protein is a member of the immunoglobulin superfamily and is likely involved in leukocyte transmigration, angiogenesis, and integrin activation.
Images
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Immunohistochemistry analysis of paraffin-embedded mouse tumor using CD31 (GB13063) at dilution of 1:100 |
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Immunohistochemistry analysis of paraffin-embedded mouse tumor using CD31 (GB13063) at dilution of 1:100 |
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Immunohistochemistry analysis of paraffin-embedded mouse tumor using CD31 (GB13063) at dilution of 1:100 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
