Your shopping cart is empty!
| Reactivity: | H |
| Applications: | IHC/IF |
| Host Species: | Mouse |
| Clonality: | Monoclonal |
| Gene Name: | Platelet endothelial cell adhesion molecule |
Synonyms: | CD31 Antigen, EndoCAM, PECAM-1, GPIIA, PECA1, CD31 |
Immunogen: | Human recombinant CD31 protein expressed in CHO cells |
Uniprot ID: | P16284 |
Isotype: | IgG2b,κ |
Purity: | Affinity purification |
Subcellular location: | Membrane, Cell junction |
Product Usage Information
IHC/IF | Human | 1: 300-1: 600 | breast cancer, gastric cancer, liver cancer |
Background
Platelet endothelial cell adhesion molecule (PECAM-1) also known as cluster of differentiation 31 (CD31) is a protein that in humans is encoded by the PECAM1 gene found on chromosome 17. PECAM-1 plays a key role in removing aged neutrophils from the body. PECAM-1 is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. The encoded protein is a member of the immunoglobulin superfamily and is likely involved in leukocyte transmigration, angiogenesis, and integrin activation.
Images
| Immunohistochemistry of paraffin embedded human gastric cancer using CD31 (GB12064) at dilution of 1: 300 (200x lens) |
| Immunohistochemistry of paraffin embedded human liver cancer using CD31 (GB12064) at dilution of 1: 300 (400x lens) |
| Immunofluorescence of paraffin embedded human breast cancer using CD31 (GB12064) at dilution of 1: 300 (100x lens) |
| Immunofluorescent analysis of paraffin embedded human lung using COLIII(GB11629) (green) + COLI(GB11022-3) (red) + Actin(GB111364) (yellow) +CD31(GB12064) (orange) at dilution of 1: 600 |
| Immunofluorescence of paraffin embedded human stomach using CD31 (GB12064) at dilution of 1: 300 (400x lens) |
| Immunofluorescent analysis of paraformaldehyde-fixed human lung cancer using Actin(GB111364) (green) + CD31(GB12064) (spred) + CD3(GB11014) (pink) at dilution of 1: 600 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
