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Anti-CD62p Rabbit pAb (100 μl)
| Reactivity: | R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | CD62p rabbit polyclonal antibody |
Gene Name: | P-selectin |
Synonyms: | CD62 antigen-like family member P, Granule membrane protein 140, GMP-140, LECAM3, Platelet activation dependent granule-external membrane protein, Leukocyte-endothelial cell adhesion molecule 3, PADGEM, CD62P, Grmp, Selp |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse CD62p |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane |
Uniprot ID: | P98106 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Rat | 1: 500-1: 1000 | bone, liver |
Background
This gene encodes a 140 kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. The membrane protein is a calcium-dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. Alternative splice variants may occur but are not well documented.
Images
| Immunohistochemistry of paraffin embedded rat bone using CD62p (GB112166) at dilution of 1:500 (400x lens) |
| Immunohistochemistry of paraffin embedded rat liver using CD62p (GB112166) at dilution of 1:500 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
