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| Reactivity: | H,M,R & H,M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Cell division control protein 42 homolog |
Synonyms: | CDC42, CDC42Hs, G25K, TKS, Cell division cycle 42, G25K, G25K GTP binding protein, Growth regulating protein, GTP binding protein 25kD, Small GTP binding protein CDC42 |
Immunogen: | Recombinant protein corresponding to Mouse CDC42 |
Uniprot ID: | P60766 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane, Cytoskeleton |
Product Usage Information
IHC/IF | Human | 1: 500-1: 3000 | liver, liver cancer, stomach |
ICC/IF | Mouse | 1: 50-1: 200 | NIH-3T3 |
Background
Cell division control protein 42 homolog, also known as Cdc42, is a protein involved in regulation of the cell cycle. Human Cdc42 is a small GTPase of the Rho family, which regulates signaling pathways that control diverse cellular functions including cell morphology, cell migration, endocytosis and cell cycle progression. Rho GTPases are central to dynamic actin cytoskeletal assembly and rearrangement that are the basis of cell-cell adhesion and migration.
Images
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Immunohistochemistry of paraffin embedded human liver using CDC42 (GB11570) at dilution of 1:1500 (400x lens) |
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Immunohistochemistry of paraffin embedded human stomach using CDC42 (GB11570) at dilution of 1:1500 (400x lens) |
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Immunofluorescence of paraffin embedded human liver cancer using CDC42 (GB11570) at dilution of 1:1000 (400x lens) |
| Immunocytochemistry analysis of 4% paraformaldehyde-fixed NIH-3T3 cells using CDC42(GB11570) at dilution of 1:50-1:200 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
