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| Reactivity: | H,M,R & H |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Cerebellar degeneration-related protein 2 |
Synonyms: | CDR2, CDR62, PCD17, Yo |
Immunogen: | Recombinant protein corresponding to Mouse CDR2 |
Uniprot ID: | P97817 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus |
Predicted MW. / Observed MW. | 52 kDa / 62 kDa |
Product Usage Information
WB | Human, Mouse, Rat | 1: 300-1: 500 | brain, kidney |
IHC/IF | Mouse | 1: 2600-1: 5200 | testis |
Background
CDR2 (cerebellar degeneration-related protein 2), also referred to as Yo or CDR62, is a 545 amino acid protein that is associated with the development of paraneoplastic cerebellar degeneration (PCD). PCD, an immune-mediated syndrome, belongs to a heterogeneous group of rare paraneoplastic neurologic disorders affecting the neurological system. PCD is characterized by subacute cerebellar ataxia and occurs mainly in patients with ovarian, uterine, fallopian tube or breast cancer.
Images
| Western blot analysis of CDR2 (GB114379) at dilution of 1: 500 |
| Immunohistochemistry analysis of paraffin embedded mouse testis using CDR2 (GB114379) at dilution of 1: 2600 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
